An NHS England (Region) is an integral part of NHS England.

NHS England (Regions) are sub-divisions of NHS England's Operations and Information Directorate.

NHS England (Regions) are responsible for:

• Providing clinical and professional leadership at sub-national level
• Co-ordinating planning, operational management and emergency preparedness where a sub-national focus is required
• Delivering improvements in the performance of health SERVICES across the NHS England (Region)
• Undertaking direct commissioning functions and processes within the single operating model
• Supporting the development of Integrated Care Boards and Integrated Care Systems.